US tops international league in action on blood products

International League of Dermatological Societies

On cusps and flat tops

We develop non-invertible Pesin theory for a new class of maps called cusp maps. These maps may have unbounded derivative, but nevertheless verify a property analogous to C. We do not require the critical points to verify a non-flatness condition, so the results are applicable to C maps with flat critical points. If the critical points are too flat, then no absolutely continuous invariant proba...

Health warnings on tobacco products: international practices.

Health warnings on tobacco products have emerged as a prominent area of tobacco control policy. Regulatory practice has rapidly evolved over the past decade to the point where health warnings on tobacco products continue to set international precedents for their size and comprehensiveness. The current paper provides a general review of current regulatory practices, including physical design fea...

Terpene/ozone Reaction Products (tops). Dependence of Irritation on Reaction Time and Relative Humidity

Earlier, we reported the formation of unidentified strong irritants in reaction mixtures of terpenes and ozone. The identified products included aldehydes, ketones and carboxylic acids. Here we report the effects of relative humidity and reaction time on irritant formation in our flow reaction system using limonene and isoprene. Upper airway irritation was measured in mice (via reduction of res...

US regulation of combination products.

The successful launch ofa combination product in the United States (US) will depend on how well a company understands applicable US regulations and policies, which differ in important ways from requirements in Europe. This article provides an overview of useful information on the US regulation of these products that can be found on the newly redesigned Food and Drug Administration website.